Red Alert: Understanding Skin Erythema

Have you ever wondered why your skin turns red ?

It might seem like a simple flush on the surface, but the process behind it is actually quite complex. Let’s unravel the science behind skin redness.

The Mechanism of Skin Redness

Skin redness, also known as erythema, is primarily caused by increased blood flow in the capillaries beneath the skin’s surface. This increased blood flow is a response to various triggers such as heat, cold, emotions, injury, or infection. When the body encounters these triggers, it sends a signal to the blood vessels to expand, allowing more blood to flow to the skin’s surface.

This makes the skin appear red !

  • Dilation of Blood Vessels: At the heart of erythema is the dilation of blood vessels, specifically the small blood vessels in the dermis, called capillaries. This process is a part of the body’s response to various stimuli, such as injury, infection, heat, or inflammation.

  • This vascular response can also be triggered by a combination of factors, for example, when we experience emotions such as shame, anger or even love, the brain’s “fight or flight” response is activated.

  • Increased Blood Flow: The dilated blood vessels allow more blood to flow through them. As a result, there is an influx of oxygenated blood to the capillaries in the skin. The oxygen-rich blood causes the skin to appear red or flushed.

  • Skin Irritation: Skin irritation occurs when the skin is subjected to stimuli that are considered as damaging or irritating. Physical causes (such as rubbing or scratching), chemical irritants, allergies, temperature extremes are examples of these stimuli leading to redness.

Take a look at the specific diseases and factors associated with skin redness,

Redness often results from inflammatory skin conditions, including:

Rosacea: Rosacea is a chronic skin condition that often leads to redness, visible blood vessels, and sometimes acne-like bumps on the face.

Eczema: Eczema is a collection of skin conditions that result in dry, itchy skin. It can affect any part of the body, it is most frequently seen on the face, hands, and feet, causing redness.

Sensitive Skin: Some people naturally have more sensitive skin, which can easily become red or irritated in response to environmental factors like temperature changes, wind, or harsh skincare products.

Allergies: Allergic reactions to skincare products or environmental allergens can lead to skin redness, itching, and inflammation.

Sunburn: Excessive sun exposure can cause skin redness and damage due to the harmful effects of UV radiation.

Now, let’s talk about something a bit more complex…

The role of pro-inflammatory cytokines in skin redness

Pro-Inflammatory Cytokines

Inflammatory cytokines are molecules produced by the body’s immune system that regulate cellular communication. These cytokines act to initiate, regulate and sustain the inflammation process.

Some cytokines clearly promote inflammation and are called “proinflammatory cytokines” for example, cytokines such as interleukin-1 (IL-1), interleukin-6 (IL-6) are key players in inflammation.

The Role of IL-8 and IL-6

Now that we have a basic understanding of why skin turns red, let’s look at the role of interleukins, specifically IL-8 and IL-6, in this process.

IL-8 : Effects of IL-8 contribute to redness and swelling, often resulting in increased blood flow and accumulation of neutrophils in the inflamed area.

IL-6 : Effects of IL-6 include processes such as dilation of blood vessels and the attraction of more immune cells to the site of inflammation.

In the context of skin redness, these interleukins cause blood vessels to dilate and promote the release of other inflammatory substances. This results in the familiar red and swollen appearance of inflamed skin.

Inhibition of proinflammatory cytokines can reduce skin inflammation in particular.

Overproduction or overactivation of these cytokines can contribute to skin problems such as dermatitis, acne, psoriasis and other inflammatory skin conditions.

Solutions and Tips for Managing Skin Redness

Inhibition of pro-inflammatory cytokines

So, if IL-8 and IL-6 are responsible for promoting inflammation and skin redness, what can be done to mitigate these effects? The answer lies in IL-8 and IL-6 inhibition.

By inhibiting the activity of pro-inflammatory cytokines, inflammation factors like IL-8 and IL-6 are reduced.

At Active Bioworks, our current research is focused on developing safe and effective ways to inhibit pro-inflammatory cytokines, bringing us one step closer to more effective treatments for skin conditions associated with redness and inflammation. So, the next time you see skin redness, remember that it is not just a rash, but a complex biological process!

With CalmActive Oat, we harnessed the power of Avena Sativa Kernel through a meticulous bio-extraction process, resulting in a potent formula that feeds the skin’s microbiome.

CalmActive Oat uses PRO-LYSATE® Technology with bioactive compounds to reduce inflammation and soothe skin. Its ß-glucan structure creates a captivating three-dimensional network that absorbs water, leaving skin calm, rejuvenated, and luminous.

We understand that inflammation can be a real downer, causing unwanted redness and itching. But fear not, because we have the perfect remedy for you.

Our innovative formula contains powerful postbiotics that work wonders in combating inflammation.

CalmActive Oat prevents the production of pro-inflammatory cytokines as IL-8 and IL-6. Skin redness and irritation will be significantly reduced with this amazing function.


Other tips for managing skin redness

  • Use Gentle Skincare Products: Opt for gentle, hypoallergenic skincare products that are specifically designed for sensitive skin. Avoid products containing alcohol, fragrances, or harsh chemicals, as these can exacerbate redness.

  • Minimize Triggers: Identify and avoid redness triggers. These may include spicy foods, hot beverages, or extreme temperatures.

  • Proper Hydration: Keeping the skin well-moisturized can help reduce redness and improve skin barrier function. Look for products with ingredients like aloe vera or lactic acid.

At this stage, let’s take a look at our another product that will be help the skin retain the moisture it needs after soothing:

Hydractive 100, the ultimate solution to combat dry and sensitive skin. We understand that lack of moisture can lead to irritation and redness, making skin feel uncomfortable and defenseless. But worry not, because Hydractive 100 is here to revolutionize your skincare routine.

At the heart of our formula lies the incredible power of aloe vera. Renowned for its numerous benefits, aloe vera is an essential ingredient in cosmetics.

Packed with vitamins, minerals, and amino acids, it nourishes and hydrates your skin like no other.

But that’s not all…

Hydractive 100 also harnesses the potential of Acemannan, a remarkable polysaccharide found in the aloe vera plant. This magical compound possesses skin structural repair properties, ensuring your skin gets the care it truly deserves.

With its unique molecular structure, Acemannan effortlessly penetrates the skin’s surface, interacting with fibroblasts to rejuvenate and revitalize your skin from within.

To summarize…

Understanding the mechanisms behind skin redness and the role of IL-8 and IL-6 can help us better manage and treat conditions characterized by this symptom. As we continue to learn more about these processes, we can look forward to more effective strategies for managing skin redness and related conditions.

To relieve skin redness and maintain skin health, cosmetic products need the right active materials. Choosing our products specially formulated for sensitive skin with the right moisturizing content, suitable for skin types, is effective in reducing redness. Products containing ingredients with anti-inflammatory properties will help calm the skin.

Have a nice and “beautiful” day!

Please don’t hesitate to reach us for more: hello@activebioworks.com

Sales Force, Active Bioworks

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