Goodbye to dandruff : M.Furfur inhibition
Microbial Balance in Hair Health: The Role of Malassezia furfur
Hair health is a process determined by the interaction of many factors. This process is influenced by various factors such as pH levels of the scalp, chemical components, and microbial balance. The overall health of the hair involves proper care of the hair follicles and scalp. In this context, the role of Malassezia furfur, a scalp microorganism, has become an important topic.
Factors Influencing Hair Health
There are many factors that affect hair health. These factors include the natural pH level of the hair, treatments with various chemical products, sebum production in the scalp and maintaining microbial balance. The balance of these factors plays a critical role in keeping the hair strong, shiny and healthy.
For example, one of the hair problems, dry hair, is usually the result of the loss of natural oils and a disturbed moisture balance. When hair strands are exposed to external factors such as heat treatments or chemical products, they can lose their natural oils.
In fact, the pH of the scalp plays an important physiological role. The pH of the stratum corneum is acidic, between 4.1 and 5.8. Disruption of the skin barrier due to increased pH can lead to skin inflammation and other epidermal diseases.
We will publish a more detailed blog on general hair health in the near future, for now let's just focus on M. furfur...
The Role of Malassezia furfur in Hair
Malassezia furfur is a type of yeast found naturally on the scalp. This microorganism plays an important role in helping to maintain healthy hair follicles and scalp. However, in case of overgrowth or when there is an imbalance, Malassezia furfur can contribute to the formation of dandruff. This type of yeast, which feeds by metabolizing sebum on the scalp, can cause dandruff and scalp problems when overgrown.
Now you may wonder - how does M. furfur affect our hair health?
The answer lies in its ability to disrupt the natural balance of our skin's ecosystem.
It is a chronic scalp condition characterized by dandruff, flaking and itching. Malassezia species are involved in the pathogenesis of dandruff, along with stress, fatigue, extreme weather conditions, oily skin, shampoo use and neurological disorders. M. furfur and M. globosa are generally recognized as causative agents of dandruff.
When M. furfur becomes overgrown, it can lead to irritation and inflammation of the scalp. This not only causes discomfort and itching, but can also interfere with the natural growth cycle of your hair. As a result, you may notice increased hair loss and slower hair growth.
Beyond these immediate effects, chronic inflammation caused by M. furfur overgrowth can damage hair follicles. This can lead to thinning hair and, in severe cases, permanent hair loss.
Therefore, controlling M. furfur is crucial for maintaining not only a healthy scalp, but also vibrant and strong hair.
Malassezia spp. and Hair Health: The Role of Lipases
Malassezia spp. is known as a pathogen dependent on host lipids. The life cycle of this microorganism is based on deficiencies in the biosynthesis of fatty acids. However, these deficiencies are compensated for by the breakdown of the host lipid and the accumulation of the resulting fatty acids. In this process, lipases, which are secreted at high levels, play an important role.
Lipases play a critical role in the pathogenicity of Malassezia. These enzymes help to extract fatty acids and provide the energy sources necessary for the microorganism to survive. Thus, elevated lipase levels are of potential importance in the pathogenicity of Malassezia spp.
In the fight against Malassezia, lowering and inhibiting lipase levels can be an effective strategy. This can keep Malassezia's proliferation in check by interfering with its vital energy sources.
Reducing lipase activity with lipase inhibitors or natural methods can maintain a healthy microbial balance of the scalp and prevent dandruff.
With specialized plant extracts and various active compounds that can help overcome the resistance of the causative organism, Active Bioworks presents ScalpActive BIO...
Our current study is an attempt at a multi-herbal blend (rich in flavanoids, phenolic compounds, tannins, etc.) for better anti-dandruff efficacy.
1) The inhibition of 5α-reductase with ScalpActive BIO is thus the most efficient way to visibly decrease sebum production.
2) Repressing Malassezia species with natural lipase inhibitor
3) Anti-fungal activity of Eucalyptus
Eucalyptus is known for its antimicrobial properties make it useful in combating Malessezia furfur on the scalp.
Last Words...
This week we focused on research on the potential of M. furfur to inhibit dandruff formation. The anti-dandruff effects of M. furfur have become a new source of hope in the dermatology and cosmetics industries.
You can contact us to get to know more closely and try these effects behind the active molecules of special plants...
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Have a nice and “beautiful” day!
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